| Solution Information | help | |
| Enzyme: | Oxytocin receptor | |
| inhibitor: | BDBM75712 | |
| substrate: | n/a | |
| Solution Type: | Aqueous | |
| pH at Preparation: | n/a | |
| Temp. Prep.: | n/a | |
| Comments: | Assay Overview: The purpose of this cell-based assay is to determine whether compounds identified as active in a set of previous experiments entitled, "Counterscreen for Oxytocin Receptor (OXTR) agonists: Fluorescence-based primary cell-based high throughput assay to identify agonists of the vasopressin 1 receptor (V1R)" (AID 2797), and "Fluorescence-based cell-based high throughput confirmation assay for agonists of the vasopressin 1 receptor (V1R)" (AID 434964), and that were inactive in a set of experiments entitled, "Counterscreen for vasopressin 1 receptor (V1R) agonists: Fluorescence-based cell-based high throughput screening assay to identify agonists of the Oxytocin Receptor (OXTR)" (AID 434969), and "Fluorescence-based primary cell-based high throughput screening assay to identify agonists of the Oxytocin Receptor (OXTR)" (AID 2435), are nonselective V1R agonists due to activation of the related GPCR, oxytocin receptor (OXTR; OTR). This assay determines OXTR (OTR) agonism do | |
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